Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABL1 All Species: 36.36
Human Site: Y185 Identified Species: 72.73
UniProt: P00519 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00519 NP_005148.2 1130 122873 Y185 T A S D G K L Y V S S E S R F
Chimpanzee Pan troglodytes XP_520319 1140 124124 Y195 T A S D G K L Y V S S E S R F
Rhesus Macaque Macaca mulatta XP_001118598 973 105035 R106 R R M V T G R R P G P H T A G
Dog Lupus familis XP_548413 1131 122978 Y185 T A S D G K L Y V S S E S R F
Cat Felis silvestris
Mouse Mus musculus P00520 1123 122654 Y185 T A S D G K L Y V S S E S R F
Rat Rattus norvegicus XP_231137 1124 122522 Y185 T A S D G K L Y V S S E S R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507150 1174 128492 Y229 T A S D G K L Y V S S E S R F
Chicken Gallus gallus XP_415463 1125 123043 Y185 T A S D G K L Y V S S E S R F
Frog Xenopus laevis NP_001084399 1102 120702 Y220 T A S D G K V Y V T A E S R F
Zebra Danio Brachydanio rerio XP_001337899 1060 117143 Y180 T A S D G K L Y V S S E S R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P00522 1620 171570 F312 E D P D G K V F V T Q E A K F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P03949 1224 138308 F252 V D N T E K M F I T Q E V K F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 78.7 91.5 N.A. 87.6 87.6 N.A. 81.6 83.6 54.2 69.9 N.A. 36.1 N.A. 33.1 N.A.
Protein Similarity: 100 97.7 81.1 93.8 N.A. 91.1 90.9 N.A. 86.2 88.4 65.4 77.2 N.A. 47 N.A. 48.9 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 100 100 80 100 N.A. 40 N.A. 20 N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 73.3 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 75 0 0 0 0 0 0 0 0 9 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 84 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 9 0 0 0 0 0 0 92 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 92 % F
% Gly: 0 0 0 0 84 9 0 0 0 9 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 92 0 0 0 0 0 0 0 17 0 % K
% Leu: 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 % L
% Met: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 9 0 9 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % Q
% Arg: 9 9 0 0 0 0 9 9 0 0 0 0 0 75 0 % R
% Ser: 0 0 75 0 0 0 0 0 0 67 67 0 75 0 0 % S
% Thr: 75 0 0 9 9 0 0 0 0 25 0 0 9 0 0 % T
% Val: 9 0 0 9 0 0 17 0 84 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _